Accredited DNA Analysis Services
Solutions for Sample Mixtures
FRISC™ for Spent Shell Casings
Center for Advanced Genomics
About Signature Science, LLC
Signature Science, LLC’s accredited forensic DNA laboratories offer state-of-the-art forensic serology, DNA analysis, and Forensic Genetic Genealogy services. We support our clients with cost-effective, scalable casework solutions for both traditional and specialized sample analysis. Further, to address the scientific and technical forensic challenges facing our criminal justice system, Signature Science engages in genomic research, development, and testing and evaluation activities in our Center for Advanced Genomics.
Casework Services
Forensic Genetic Genealogy
No Match in CODIS?
Consider this Next Step.
Forensic genetic genealogy (FGG) is a different approach to develop investigative leads for your cold case or active case that has not returned a DNA match in the CODIS database. FGG uses advanced DNA workflows to generate a SNP profile for upload to public genetic genealogy database(s) authorized for law enforcement use to search for familial links. MORE
Forensic DNA Analysis
Our casework laboratories deliver high-quality analyses to our clients at the federal, state, and local levels. On-time. Every time.
Case and Data Review
Meet with us and walk our experts through the details of your case. We’ll help you uncover the best, most cost-effective evidence testing plan.
Expert Witness Testimony
Each analyst involved in your case is trained and adept at delivering expert witness testimony that juries can understand.
Shell Casing Analysis
Our approach to DNA recovery from spent shell casings maximizes DNA recovery without compromising downstream ballistics testing.
Resources
Signature Science’s experts advance the capabilities of forensic science applications with research and development of new methods and laboratory automation software. To support the continuous improvement of forensic laboratory operations, we offer technical workshops, presentations, and tailored training.
Center for Advanced Genomics®
In our Center for Advanced Genomics®, we develop and validate novel methods for maximizing DNA recovery in both yield and quality from challenging samples. We evaluate and optimize sequencing and genotyping technologies for forensic applications.
Bioinformatics Tools
Our bioinformaticians develop tailored workflow tools and solutions to achieve automation objectives for forensic laboratory operations.
Research & Technical Presentations
Our DNA analysts and forensic scientists contribute to the forensic science community through workshops and presentations on impactful topics.
Training & Validation Services
Our training courses and validation services are tailored to the needs of individual laboratories, departments, and agencies.
Funding Resources
Several federal programs offer law enforcement and non-profit organizations funding support at the local and state level.
For a great collection of informative presentations, visit Research & Technical Presentations.
Forensic DNA News
Horizon Newsletter – July 2025
We’re excited to launch our new dedicated forensics website designed to make working with Signature Science easier and more efficient than ever before! The new website features: Comprehensive Forensic DNA Testing Services – In-depth information on our full suite of forensic DNA testing capabilities Streamlined … MORE
Our Interns’ Summer with SigSci Forensics
Each summer, Signature Science, LLC welcomes at least one intern to assist with research in our Center for Advanced Genomics (CAG). The research and validations performed at the CAG are shared with the forensic community in the form of open-source … MORE
Horizon Newsletter – April 2025
Accredited FGG Services to Better Serve You! Signature Science’s Advanced Genomics Laboratory has been accredited by the ANSI National Accreditation Board (ANAB) to the ISO/IEC 17025:2017 quality standard for forensic testing of Single-Nucleotide Polymorphisms (SNPs). As part of the accreditation process, our … MORE