Accredited DNA Analysis Services
Solutions for Sample Mixtures
FRISC™ for Spent Shell Casings
Center for Advanced Genomics
About Signature Science, LLC
Signature Science, LLC’s accredited forensic DNA laboratories offer state-of-the-art forensic serology, DNA analysis, and Forensic Genetic Genealogy services. We support our clients with cost-effective, scalable casework solutions for both traditional and specialized sample analysis. Further, to address the scientific and technical forensic challenges facing our criminal justice system, Signature Science engages in genomic research, development, and testing and evaluation activities in our Center for Advanced Genomics.

Casework Services
Forensic Genetic Genealogy
No Match in CODIS?
Consider this Next Step.
Forensic genetic genealogy (FGG) is a different approach to develop investigative leads for your cold case or active case that has not returned a DNA match in the CODIS database. FGG uses advanced DNA workflows to generate a SNP profile for upload to public genetic genealogy database(s) authorized for law enforcement use to search for familial links. MORE


Forensic DNA Analysis
Our casework laboratories deliver high-quality analyses to our clients at the federal, state, and local levels. On-time. Every time.

Case and Data Review
Meet with us and walk our experts through the details of your case. We’ll help you uncover the best, most cost-effective evidence testing plan.

Expert Witness Testimony
Each analyst involved in your case is trained and adept at delivering expert witness testimony that juries can understand.

Shell Casing Analysis
Our approach to DNA recovery from spent shell casings maximizes DNA recovery without compromising downstream ballistics testing.
Resources
Signature Science’s experts advance the capabilities of forensic science applications with research and development of new methods and laboratory automation software. To support the continuous improvement of forensic laboratory operations, we offer technical workshops, presentations, and tailored training.

Center for Advanced Genomics®
In our Center for Advanced Genomics®, we develop and validate novel methods for maximizing DNA recovery in both yield and quality from challenging samples. We evaluate and optimize sequencing and genotyping technologies for forensic applications.

Bioinformatics Tools
Our bioinformaticians develop tailored workflow tools and solutions to achieve automation objectives for forensic laboratory operations.

Research & Technical Presentations
Our DNA analysts and forensic scientists contribute to the forensic science community through workshops and presentations on impactful topics.

Training & Validation Services
Our training courses and validation services are tailored to the needs of individual laboratories, departments, and agencies.

Funding Resources
Several federal programs offer law enforcement and non-profit organizations funding support at the local and state level.

For a great collection of informative presentations, visit Research & Technical Presentations.
Forensic DNA News
Signature Science Achieves ISO/IEC 17025:2017 Accreditation for Massively Parallel Sequencing (MPS)
Achievement builds on Company’s forensic science laboratory’s accreditation scope and expands its accredited offerings into the Forensic Genetic Genealogy space. AUSTIN, TEXAS – February 25, 2025 – Signature Science’s Advanced Genomics Laboratory has been issued accreditation by ANAB, the ANSI National … MORE
Horizon Newsletter – February 2025
Laboratory Leadership at AAFS Documentary standards play a critical role in ensuring consistency, quality, and credibility in forensic science. Hosted in collaboration with Travis County Medical Examiner’s Office, our Deep-Dive session at AAFS will explore the importance of standards development, how … MORE
Published in “FSI Genetics”: MixDeR: A SNP mixture deconvolution workflow for forensic genetic genealogy Abstract: The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. … MORE