Horizon Newsletter – May 2026

Signature Science has validated a SNP mixture deconvolution workflow for two-person DNA mixtures, a breakthrough enabling new leads from evidence previously unusable. When a sample contains DNA from two contributors, our process separates the mixture to produce a single-source SNP profile for the major contributor, making it suitable for forensic investigative genetic genealogy (FIGG) analysis.

The advent of this technology means that more evidence types can be considered for FIGG. Critically, depending on the mixture ratio, our workflow can be used with or without a reference sample.

Unsure if your sample is a good fit? Leave it to us! We will evaluate your evidence and work closely with your team to develop a testing plan that maximizes the investigative potential of your case, whether it’s a decades-old cold case or an active investigation.

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