Authorized Statement on the Yogurt Shop Murders Investigation
October 07, 2025 – After over 30 years, breakthroughs in forensic science have led investigators to identify a person of interest in the 1991 murders of four young Austin-area girls; Eliza Thomas, Amy Ayers, and sisters Jennifer Harbison and Sarah Harbison. Announced at a media briefing held by the City of Austin on Monday, 9/29, this development in the “Yogurt Shop Murders” case represents the outcome of years of tireless commitment, open communication, and coordinated efforts across the forensic and law enforcement communities. In keeping with our confidentiality policies and professional obligations, Signature Science does not comment on specific cases without … MORE
Horizon Newsletter – July 2025
We’re excited to launch our new dedicated forensics website designed to make working with Signature Science easier and more efficient than ever before! The new website features: Comprehensive Forensic DNA Testing Services – In-depth information on our full suite of forensic DNA testing capabilities Streamlined … MORE
Our Interns’ Summer with SigSci Forensics
Each summer, Signature Science, LLC welcomes at least one intern to assist with research in our Center for Advanced Genomics (CAG). The research and validations performed at the CAG are shared with the forensic community in the form of open-source … MORE
Horizon Newsletter – April 2025
Accredited FGG Services to Better Serve You! Signature Science’s Advanced Genomics Laboratory has been accredited by the ANSI National Accreditation Board (ANAB) to the ISO/IEC 17025:2017 quality standard for forensic testing of Single-Nucleotide Polymorphisms (SNPs). As part of the accreditation process, our … MORE
Signature Science Achieves ISO/IEC 17025:2017 Accreditation for Massively Parallel Sequencing (MPS)
Achievement builds on Company’s forensic science laboratory’s accreditation scope and expands its accredited offerings into the Forensic Genetic Genealogy space. AUSTIN, TEXAS – February 25, 2025 – Signature Science’s Advanced Genomics Laboratory has been issued accreditation by ANAB, the ANSI National Accreditation Board, to the ISO/IEC 17025:2017 quality standard as a testing laboratory for Single-Nucleotide Polymorphisms (SNPs) using Massively Parallel Sequencing (MPS). A laboratory assessment conducted by ANAB revealed no instances of non-conformance. In addition, the laboratory was successfully assessed for conformance to FBI Quality Assurance Standards for Forensic Testing Laboratories.Signature Science has optimized and validated methods for obtaining DNA profiles … MORE
Horizon Newsletter – February 2025
Laboratory Leadership at AAFS Documentary standards play a critical role in ensuring consistency, quality, and credibility in forensic science. Hosted in collaboration with Travis County Medical Examiner’s Office, our Deep-Dive session at AAFS will explore the importance of standards development, how … MORE
Published in “FSI Genetics”: MixDeR: A SNP mixture deconvolution workflow for forensic genetic genealogy Abstract: The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. … MORE
January 29, 2025 • A press release issued by LMI Group International, Inc. detailed the conclusion of multi-year, interdisciplinary investigation to authenticate a painting and attribute it to the artist, Vincent van Gogh. The investigation combined traditional authentication and innovative scientific methods. During … MORE
An Investigation of Downstream Processing Methods for Challenging Skeletal Samples
Abstract: While skeletal remains are known for their resilience and often serve as the final source of information for unidentified human remains (UHRs), the traditional downstream processing of these samples is challenging due to their low template nature, DNA degradation, … MORE
HORIZON Newsletter – November 2024
Sample mixtures and the ability to deconvolute SNP profiles present a challenge for investigations using FGG. These mixtures are common in forensics, however, database search algorithms utilized for FGG only accommodate single-source SNP profiles. To address this gap, NBFAC and … MORE
MixDeR: A SNP Mixture Deconvolution Workflow for Forensic Genetic Genealogy
Abstract: The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. At the same time, and in part because of this advance, there … MORE