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Horizon Newsletter – July 2025

We’re excited to launch our new dedicated forensics website designed to make working with Signature Science easier and more efficient than ever before!  The new website features: Comprehensive Forensic DNA Testing Services – In-depth information on our full suite of forensic DNA testing capabilities Streamlined Communication – Simplified case submission and contact forms Reference Documentation at Your Fingertips – Easy access to our accreditation certificates Knowledge Center- A regularly updated repository library of publications, technical presentations, and research outputs Coming Soon: The Signature Science Customer Hub Your one-stop shop for all files and documentation related to your case. View full Horizon Newsletter and sign up for future updates here. MORE

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Our Interns’ Summer with SigSci Forensics

Each summer, Signature Science, LLC welcomes at least one intern to assist with research in our Center for Advanced Genomics (CAG). The research and validations performed at the CAG are shared with the forensic community in the form of open-source … MORE

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Horizon Newsletter – April 2025

Accredited FGG Services to Better Serve You! Signature Science’s Advanced Genomics Laboratory has been accredited by the ANSI National Accreditation Board (ANAB) to the ISO/IEC 17025:2017 quality standard for forensic testing of Single-Nucleotide Polymorphisms (SNPs). As part of the accreditation process, our … MORE

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Signature Science Achieves ISO/IEC 17025:2017 Accreditation for Massively Parallel Sequencing (MPS)

Achievement builds on Company’s forensic science laboratory’s accreditation scope and expands its accredited offerings into the Forensic Genetic Genealogy space. AUSTIN, TEXAS – February 25, 2025 – Signature Science’s Advanced Genomics Laboratory has been issued accreditation by ANAB, the ANSI National … MORE

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Horizon Newsletter – February 2025

Laboratory Leadership at AAFS Documentary standards play a critical role in ensuring consistency, quality, and credibility in forensic science. Hosted in collaboration with Travis County Medical Examiner’s Office, our Deep-Dive session at AAFS will explore the importance of standards development, how the process works, and the benefits of becoming actively involved. Attendees will gain insights into how contributing to standards development can enhance analytical and problem-solving skills, strengthen leadership abilities, and provide opportunities for professional growth. The session will also highlight how this work supports the broader forensic community by promoting scientifically sound practices and advancing the field. View the full Horizon newsletter … MORE

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Published in “FSI Genetics”: MixDeR: A SNP mixture deconvolution workflow for forensic genetic genealogy

Published in “FSI Genetics”: MixDeR: A SNP mixture deconvolution workflow for forensic genetic genealogy Abstract: The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. … MORE

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Report Details Signature Science Contributions to LMI Group’s Efforts to Authenticate  “Elimar” (1889)

January 29, 2025 • A press release issued by LMI Group International, Inc. detailed the conclusion of multi-year, interdisciplinary investigation to authenticate a painting and attribute it to the artist, Vincent van Gogh. The investigation combined traditional authentication and innovative scientific methods. During … MORE

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An Investigation of Downstream Processing Methods for Challenging Skeletal Samples

Abstract: While skeletal remains are known for their resilience and often serve as the final source of information for unidentified human remains (UHRs), the traditional downstream processing of these samples is challenging due to their low template nature, DNA degradation, … MORE

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HORIZON Newsletter – November 2024

Sample mixtures and the ability to deconvolute SNP profiles present a challenge for investigations using FGG. These mixtures are common in forensics, however, database search algorithms utilized for FGG only accommodate single-source SNP profiles. To address this gap, NBFAC and … MORE

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An Interview with Friends who Found Each Other Through Forensic Science

In October, we sat down with Natalie Collins, Belinda Reyes, and Samantha Guigliemi, analysts in our Forensic Laboratory in Austin, TX. These three share a close friendship that has flourished in their time a Signature Science. We wanted to get … MORE

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MixDeR: A SNP Mixture Deconvolution Workflow for Forensic Genetic Genealogy

Abstract: The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. At the same time, and in part because of this advance, there … MORE

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